专职PI
苏锋涛 副研究员
副研究员,博士
E-mail: sufengtao@126.com
 

  苏锋涛博士,2010年毕业于中国科学院近代物理研究所。2010-2015年在美国德州大学西南医学中心放射肿瘤学系做博士后研究。2016年至今在复旦大学附属肿瘤医院肿瘤研究所工作。长期从事肿瘤发生及肿瘤放射生物学机制研究。在Cell Reports、Oncotarget、Radiation Oncology等刊物发表论文多篇。


研究领域:

  1.DNA复制损伤和肿瘤发生的机制研究;
  2.DNA损伤和修复的分子机理研究;
  3.肿瘤放疗标记物的筛选和相关机制研究;
  4.肿瘤微环境和肿瘤放疗;
  5.重离子治癌机理研究。


代表性论著:

  1. Fengtao Su#, Hirohiko Yajima, Shibani Mukherjee, Steven M Yannone, Benjamin P Chen, David J Chen, Aroumougame Asaithamby. Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway.Oncotarget, 2016 Jan 5; 7(1):46-65. 
  2. Jiayun Zhu, Fengtao Su, Shibani Mukherjee, Eiichiro Mori, Burong Hu, Aroumougame Asaithamby. FANCD2 influences replication fork processes and genome stability in response to clustered DSBs. Cell Cycle, 2015; 14(12):1809-22.
  3. Fengtao Su#, Shibani Mukherjee, Yanyong Yang, Eiichiro Mori, Souparno Bhattacharya, Junya Kobayashi, Steven M. Yannone, David J. Chen, Aroumougame Asaithambyemail. Nonenzymatic Role for WRN in Preserving Nascent DNA Strands after Replication Stress. Cell Reports, 2014 Nov 20; 9(4):1387-401.
  4. Gerelchuluun A, Zhu Jiayun, Su Fengtao, Asaithamby A, Chen DJ, Tsuboi K. Homologous recombination pathway may play a major role in high-LET radiation-induced DNA double-strand break repair. J. Radiation Research, 3, 2014.
  5. Jufang Wang, Jinpeng He, Fengtao Su, Nan Ding, Wengtao Hu, Bin Yao, Wei Wang and Guangming Zhou. Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition. Cell Death and Disease, 2013 Jun 27; 4:e699.
  6. Jufang Wang, Fengtao Su, Lubomir B Smilenov, Libin Zhou, Wentao Hu, Nan Ding, and Guangming Zhou. Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity. Radiation Oncology, 2011 Aug 17; 6:96. 
  7. Fengtao Su#, Lubomir B Smilenov, Thomas Ludwig, Libin Zhou, Jiayun Zhu, Guangming Zhou and Eric J Hall. Hemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis. Radiation Oncology, 2010 Feb 22; 5:15.
  8. Feng-tao Su#, Qiang Li, Xiao-dong JIN. Biological Effects of H1299 Cells Exposed to 12C Ion Beam and X-rays. Nuclear Physics Review, 2008; 25 (1): 72-76.
 
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